Genetic mosaicism can occur in any tissue, but is particularly apparent in the skin. Since Blaschko described his lines in 1901 and Happle attributed them to genetic mosaicism in the 1970s, cutaneous mosaicism has become mainstream. This lecture will explore the variety of dermatological presentations of genetic mosaicism with implications for diagnosis and management.

Reference: Moss C, Brown F. Chapter 62 Mosaicism and linear lesions. in Dermatology eds Bolognia JL, Schaffer JV, Cerroni L. Fourth Ed 2018, Elsevier